Pharmaceutical Technology

A Prototype Intelligent Hybrid System for Hard Gelatin Capsule Formulation Development

Mintong Guo, Gunjan Kalra, Wendy Wilson, Yun Peng, and Larry L Augsburger

September 1, 2002

Although hard gelatin capsules are perceived to be a simple dosage form, the design of formulations for the capsules can present significant challenges.The authors have created a prototype hybrid system by linking a decision module (ES) with a prediction module (ANN) capable of yielding formulations of a model BCS Class II drug.

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Type: Article

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